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. Author manuscript; available in PMC: 2021 Nov 17.
Published in final edited form as: J Med Chem. 2021 Oct 27;64(21):15991–16007. doi: 10.1021/acs.jmedchem.1c01383

Table 1.

Structures, cLogP Values, and Antimycobacterial Minimum Inhibitory Concentration (MIC) Values of Series 1–6 Compounds on M. bovis Bacillus Calmette-Guerin (BCG)

graphic file with name nihms-1752980-t0002.jpg graphic file with name nihms-1752980-t0003.jpg
a

Minimum inhibitory concentration required to reduce growth by 90% compared to untreated controls. Mean (±SD) of n = 3 separate determinations. For n = 2, the value of each determination is indicated. MIC90’s of clofazimine and isoniazid (INH) were 0.40 and 3.2 μM, respectively.

b

cLogP is an estimate of lipophilicity, and values were determined using ChemDraw Professional Version 15.1.0.144.