Table 3.

ICV- and Age-corrected Brain Volumes (cc) for CTRL, AUD, AUD-noDrugHx, and AUD+DrugHx (mean, sd)

	CT RL	AUD	t, p- value	AUD- noDrugH x	AUD+ DrugH x	t, p-value: AUD subgroups
Frontal ROIs	(n=36)	(n=91)		(n=42)	(n=49)
precentral	18.51	17.38	t=3.13, p=.002	17.86	16.96	t=2.72, p=.026
	(1.65)	(1.91)		(1.70)	(2.00)
superior	19.21	19.29	t=0.24, p=.808	19.45	19.16	t=0.76, p=.450
	(1.46)	(1.81)		(1.96)	(1.69)
orbital	26.38	26.10	t=0.69, p=.490	26.19	26.03	t=0.35, p=.726
	(1.77)	(2.14)		(1.96)	(2.31)
middle	25.92	25.18	t=1.80, p=.074	25.23	25.14	t=0.20, p=.840
	(1.88)	(2.16)		(2.05)	(2.26)
inferior	24.14	23.78	t=1.09, p=.277	24.16	23.45	t=1.97, p=.052
	(1.49)	(1.75)		(1.57)	(1.84)
supplementary motor	11.45	11.18	t=1.04, p=.299	11.51	10.90	t=2.21, p=.029
	(1.12)	(1.34)		(1.24)	(1.37)
medial	24.91	24.69	t=0.66, p=.511	24.99	24.44	t=1.65, p=.102
	(1.85)	(1.59)		(1.54)	(1.61)
Hippocampus	8.76	8.51	t=2.10, p=.038	8.46	8.55	t=0.82, p=.413
	(0.72)	(0.56)		(0.56)	(0.56)