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. 2021 Nov 16;11:22348. doi: 10.1038/s41598-021-01710-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Coupling strength (vertical axis) across 8 time windows (horizontal axis) between RRI and respiratory signal (A) for one representative participant in the frequency band of 0.05 to 0.15 Hz; dominant flow from respiration to RRI, characteristic for positive RSA, is documented. Coupling strength between BOLD signals from brainstem rostral pons structure (ponsr, ROI 93) and PCG from another participant (B).