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. 2021 Nov 16;11:590. doi: 10.1038/s41398-021-01680-5

Table 1.

Significant GWAS results (p < 1.0 × 10−6) for entorhinal cortical thickness and hippocampal volume adjusted for APOE genotype.

Trait Chr Position SNP MA MAF IQS β SE p-value Locus
Entorhinal thickness 8 145154282 rs77359862 A 0.01 G −0.59 0.10 5.0 × 10−9 SHARPIN
14 27221601 rs7160806 G 0.39 0.992 −0.13 0.02 7.1 × 10−7 NOVA1-AS1
14 27219914 rs1956822 G 0.39 0.995 −0.13 0.02 5.8 × 10−7 NOVA1-AS1
Hippocampal volume 8 145154282 rs77359862 A 0.01 G −0.62 0.09 5.1 × 10−12 SHARPIN
8 144984345 rs80120848 A 0.01 G −0.53 0.10 2.3 × 10−8 EPPK1/PLEC
18 48554594 rs150912768 T 0.01 0.953 −0.45 0.09 6.9 × 107 SMAD4/ELAC1

Chr chromosome, MA minor allele, MAF minor allele frequency, IQS imputation quality score, G genotyped SNP, SE standard error