Table 5.
Multivariable ordinal logistic regression models to predict proportion of rural clinical trial participants a
| Model | Participants from Arizona b | Participants from Florida b | Risk factors | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Blood draw c | Drugs or biological agents c | Drugs or biological agents requiring FDA review c | Medical or educational records c | Ionizing radiation c | Any invasive procedure c | Medical devices c | Medical devices requiring FDA review c | |||
| Model 1 | −2 (0.3); <.0001 | −1 (0.3); .0002 | 0.1 (0.4); .8 | NA | NA | NA | NA | NA | NA | NA |
| Model 2 | −2 (0.3); <.0001 | −1 (0.3); .0003 | NA | −0.3 (0.3); .3 | NA | NA | NA | NA | NA | NA |
| Model 3 | −2 (0.3); <.0001 | −1 (0.3); .0003 | NA | NA | 0.3 (0.3); .4 | NA | NA | NA | NA | NA |
| Model 4 | −2 (0.3); <.0001 | −1 (0.3); .0003 | NA | NA | NA | 0.2 (0.2); .4 | NA | NA | NA | NA |
| Model 5 | −2 (0.3); <.0001 | −1 (0.3); .0003 | NA | NA | NA | NA | −0.3 (0.2); .2 | NA | NA | NA |
| Model 6 | −2 (0.3); <.0001 | −1 (0.3); .0002 | NA | NA | NA | NA | NA | 0.2 (0.2); .3 | NA | NA |
| Model 7 | −2 (0.3); <.0001 | −1 (0.3); .0002 | NA | NA | NA | NA | NA | NA | 0.2 (0.3); .4 | NA |
| Model 8 | −2 (0.3); <.0001 | −1 (0.3); .0002 | NA | NA | NA | NA | NA | NA | NA | 0.3 (0.4); .5 |
| Model 9 | −2 (0.3); <.0001 | −1 (0.3); .0002 | 0.5 (0.5); .3 | −0.5 (0.5); .3 | 0.3 (0.3); .3 | 0.08 (0.2); .8 | −0.3 (0.2); .2 | 0.3 (0.2); .1 | 0.004 (0.4); .9 | 0.1 (0.5); .8 |
FDA, US Food and Drug Administration; NA, not applicable.
a
Values are “parameter estimate (standard error); P value.” Models 1–8 are for individual risk factors; Model 9 includes all risk factors.
b
Reference group = participants at Mayo Clinic in the Midwest.
c
Risk factors.