Fig. 5.

Effect of QUE on the behavioral performance of NAFLD rats in the OFT and MWM. The data are presented as the mean ± SEM, with 8 rats in each of the groups. In the OFT, there was no significant difference among groups with respect to the frequency of rearing, grooming or defecation (a). In the MWM, the escape latency of the NAFLD rats was longer than that of the control or CON+QUE rats on all 3 days of the acquisition phase (b). In the probe trial, NAFLD rats spent less time than control or CON+QUE rats in the target quadrant (c). These abnormalities could be reversed by treatment with QUE. ^**P < 0.01 compared with the control group. ^#P < 0.05 and ^##P < 0.01 compared with the NAFLD model group