Fig. 5.

Concerti fishplot and tumor evolution tree T for patient CLL2 multi-time data. The fishplot width corresponds to approximate tumor size using ALC values. Clones are colored and sized proportionally to their prevalence. The corresponding tumor tree is aligned by timepoint and highlights to the birth of brown clone, which occurred prior to the annotation of clinical relapse. Node sizes correspond to prevalence. The edges of the T are labeled by the known cancer genes and the colors denote the distinct pseudoclones estimated by Concerti. Red asterisk indicates acquisition of new alterations to clone