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The autochthonous LSL:EGFR T790M/L858R model develops lung adenocarcinoma in mice. A) Schematic of mouse model with LoxP‐mediated activation of EGFR T790M/L858R mutations. B) Overall survival of mice of the indicated gender is graphed, n = 7 male, n = 13 female. C) Representative H&E stained cross sections from lungs of EGFR T790M/L858R autochthonous model. D) Representative immunofluorescence staining of EGFR T790M/L858R autochthonous lung tumors with the indicated probes.
