Table 2.
Genotype distribution of CYP2E1*1B, *5B, and *6 in 140 Saudi subjects.
| SNP | Genotype | Total (n = 140) | Observed Frequency% (95% CI) |
Observed/Expected frequencies (under the HW law) | P value for HW equilibrium |
|---|---|---|---|---|---|
| CYP2E1*1B | A2A2 | 76 | 54.29 (43.71 to 64.02) | 0.98 |
0.57 |
| A2A1 | 56 | 40 (21.26 to 36.81) | 1.05 | ||
| A1A1 | 8 | 5.71 (1.59 to 0.90) | 0.86 | ||
| CYP2E1*5B | c1c1 | 139 | 99.93 (96.08 to 99.98) | 1.00 |
0.97 |
| c1c2 | 1 | 0.07 (0.02 to 3.92) | 1.00 | ||
| c2c2 | 0 | 0.00 (0) | 0.00 | ||
|
CYP2E1*6 |
DD | 128 | 91.43 (56.49 to 72.86) | 1.41 |
0.18 |
| DC | 11 | 7.85 (3.99 to 13.62) | 0.88 | ||
| CC | 1 | 0.72 (0.02 to 3.92) | 1.05 |
SNP: Single nucleotide polymorphism. CI: Confidence interval. HW: Hardy-Weinberg.