Figure 3. Perforated plate made of patented original titanium alloy, removed 1 month after intracranial implantation to New Zealand white rabbits.

Connective tissue capsule forming around the plate: (a) general view of the plate with surrounding tissues, ×100; blood vessels and multiple cells of the surrounding tissue: (b) ×250; (c) ×1000; numerous macrophages in the focus of productive inflammation: (d) ×1000; (e) ×2500; (f) ×5000