. Author manuscript; available in PMC: 2022 Nov 1.

Published in final edited form as: Contemp Clin Trials. 2021 Sep 20;110:106571. doi: 10.1016/j.cct.2021.106571

Table 8.

Bias of expected estimated posterior ePTB rate $E ({\hat{p}}_{d} | data)$

Scenario	Model	Dose(g/day)						Average
Scenario	Model	0	0.2	0.45	0.6	0.8	1	Average
Optimistic	EMAX Mixture	0.0004	−0.0013	0.0000	0.0008	0.0017	0.0024	0.0007
	EMAX logistic	0.0011	−0.0013	−0.0002	0.0005	0.0013	0.0019	0.0005
	Independent logistic	−0.0001	0.0000	0.0001	−0.0001	−0.0001	0.0000	0.0000
Expected	EMAX Mixture	0.0019	−0.0013	−0.0005	0.0003	0.0013	0.0021	0.0006
	EMAX logistic	0.0016	−0.0014	−0.0005	0.0004	0.0014	0.0022	0.0006
	Independent logistic	−0.0001	0.0000	0.0001	−0.0001	−0.0001	−0.0001	0.0000
Pessimistic	EMAX Mixture	0.0014	−0.0007	−0.0002	0.0002	0.0007	0.0011	0.0004
	EMAX logistic	0.0012	−0.0006	0.0001	0.0005	0.0010	0.0015	0.0006
	Independent logistic	0.0000	0.0000	−0.0001	0.0000	0.0000	0.0000	0.0000
No effect	EMAX Mixture	0.0016	0.0004	0.0000	−0.0002	−0.0002	−0.0003	0.0002
	EMAX logistic	0.0020	0.0005	−0.0001	−0.0002	−0.0002	−0.0001	0.0003
	Independent logistic	−0.0001	0.0001	0.0000	0.0001	−0.0002	0.0000	0.0000