Table 3.
Baseline Static Perimetry –Reliability Measures Within Test Session and Variability Among Sessions Data
| Clinical Diagnosis | |||
|---|---|---|---|
| Overall N =126a | USH2 N=80 | ARRP N=46 | |
|
| |||
| Reliability Factor (%) b | |||
| Median (IQR) | |||
|
| |||
| Overall | 5.1 (2.6, 8.2) | 5.2 (2.1, 9.1) | 5.1 (3.0, 7.3) |
| Test 1 | 4.7 (1.9, 9.0) | 4.2 (1.7, 8.8) | 5.1 (2.8, 9.8) |
| Test 2 | 4.7 (2.5, 9.8) | 5.1 (2.4, 11.1) | 4.6 (2.6, 7.2) |
| Test 3 | 5.0 (2.4, 9.0) | 5.4 (2.3, 9.4) | 4.5 (2.6, 8.8) |
|
| |||
| False positives rate (%) b | |||
| Median (IQR) | |||
|
| |||
| Overall | 1 (0, 3) | 1 (0, 4) | 2 (0, 3) |
| Test 1 | 0 (0, 4) | 0 (0, 4) | 1 (0, 3) |
| Test 2 | 0 (0, 3) | 0 (0, 5) | 0 (0, 3) |
| Test 3 | 0 (0, 5) | 0 (0, 5) | 0 (0, 4) |
|
| |||
| False negatives rate (%) b | |||
| Median (IQR) | |||
|
| |||
| Overall | 8 (3, 14) | 8 (2, 15) | 8 (5, 11) |
| Test 1 | 6 (3, 15) | 6 (0, 13) | 8 (3, 15) |
| Test 2 | 7 (3, 16) | 8 (3, 19) | 7 (3, 13) |
| Test 3 | 7 (3, 17) | 7 (2, 17) | 7 (3, 14) |
|
| |||
| Intraclass correlation coefficient (95% confidence interval) c | |||
| Overall (tests 1,2, and 3) | 0.96 (0.94 0.97) | Not applicable | |
| Tests 1 and 2 | 0.98 (0.97 0.98) | Not applicable | |
| Tests 2 and 3 | 0.95 (0.93 0.97) | Not applicable | |
| Tests 1 and 3 | 0.94 (0.92 0.96) | Not applicable | |
|
| |||
| Repeatability coefficient (95% confidence interval) c | |||
| Overall (tests 1,2, and 3) | 13.7 (9.2, 16.3) | Not applicable | |
a
Static perimetry results were graded by a reading center. 1 participant in ARRP group was missing all SP tests and is excluded from this table.
b
Test 2 and Test 3 data are not included for 24 participants, respectively (22 secondary cohort participants only performed the test once, and 2 primary cohort participants were missing the second and the third test)
c
Variability analysis data are not included for 25 participants (22 secondary cohort participants only performed the test once, and 2 primary cohort participants were missing the second and the third test, and 1 participant was missing the third VTOT value.)