Figure 7.
Evidence for independent Denisovan introgression event into Philippine Negritos
(A and B) Empirical evidence for higher Denisovan ancestry in Ayta relative to Papuans estimated by f4-ratio statistics on genotyped data (A) and S’ method on sequence data (B).
(C) Mean Denisovan tracts lengths in Ayta Magbukon versus Papuans.
(D) Ratio of Denisovan ancestry over Australasian ancestry in Ayta-related and Papuan-related populations.
(E) Correlation between Denisovan ancestry and Australasian ancestry, where Negritos (red line) fall outside the slope of the Papuan cline (blue line).
(F–Ad) Diagram for the null (F), alternative models 1–4 (K, P, U, and Z) indicating the number and the time of archaic introgression events into Ayta Negritos and Papuans, simulated using msprime (see STAR Methods), with the respective estimated levels of Denisovan ancestry (G, L, Q, V, and Aa), mean Denisovan tract length (H, M, R, W, and Ab), ratio of Denisovan ancestry over Australasian ancestry (I, N, S, X, and Ac), and correlation between Denisovan ancestry and Australasian ancestry (J, O, T, Y, and Ad). Australasian ancestry was estimated using qpAdm. All pairwise comparisons were tested for significance using the Mann-Whitney U test with Holm-Bonferroni correction. Error bars represent standard error of the mean.