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Cancer testis antigen and major histocompatibility complex I expression in high grade urothelial carcinoma. Expression of A. CT10 and B. PRAME in high grade urothelial carcinoma; note the nuclear expression in tumour cells and lack of expression in background stromal/inflammatory cells. C. Retained/normal MHC I expression, compared to D. complete lack of MHC I expression; note the retained expression in background stromal/inflammatory cells. Scale bar = 300 micrometers
