Table 1.
Biomarkers and characteristics of MSCs derived from different sources
| MSCs isolated from different sources | Presence | Absence | Characteristics | References |
|---|---|---|---|---|
| Bone marrow | CD13, CD44, CD73, CD90, CD105, CD166, STRO-1 | CD14, CD34, CD45, HLA-DR | Confirmed safety | [184–186] |
| Capacity to differentiate into hepatocyte | ||||
| Adipose tissue | CD71, CD9, CD13, CD29, CD44, CD54, CD73, CD90, CD105, CD106, CD146, CD166, HLA I, STRO-1 | CD14, CD19, CD31, CD34, CD45, CD133, HLA-DR | Abondance in adipose tissue | [184, 187–190] |
| Have weaker differentiating potential towards osteocytes and chondrocytes | ||||
| Birth-derived tissues | CD29, CD44, CD73, CD90, CD105, CD146 | CD14, CD34, CD45 | Have relatively high proliferation rate | [191–193] |
| Produce more insulin than bone marrow MSC | ||||
| Dental pulp | CD29, CD44, CD90, CD105 | CD14, CD34, CD45 | Have odontoosteogenic properties | [194–196] |
| Locate within the dental crown | ||||
| Peripheral blood | CD44, CD54, CD90, CD105, CD166, HLA-ABC | CD14, CD34, CD45, CD31 | Manifest similar immunophenotypes and differentiation potential to those of bone marrow MSC | [197–199] |
| The volume of blood is large | ||||
| Endometrium | CD73, CD90, CD105, CD146 | CD34, CD45 | Have the potential of mesodermal lineage differentiation | [197, 200, 201] |
| Producing high level of leukemia inhibitory factors | ||||
| Skin | CD44, CD73, CD90, CD105, CD166, CD29 | CD34, CD45, HLA-DR | Have higher proliferation rate than that of adipose MSC | (202–204) |