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. 2021 Nov 17;14:195. doi: 10.1186/s13045-021-01208-w

Table 1.

Biomarkers and characteristics of MSCs derived from different sources

MSCs isolated from different sources Presence Absence Characteristics References
Bone marrow CD13, CD44, CD73, CD90, CD105, CD166, STRO-1 CD14, CD34, CD45, HLA-DR Confirmed safety [184186]
Capacity to differentiate into hepatocyte
Adipose tissue CD71, CD9, CD13, CD29, CD44, CD54, CD73, CD90, CD105, CD106, CD146, CD166, HLA I, STRO-1 CD14, CD19, CD31, CD34, CD45, CD133, HLA-DR Abondance in adipose tissue [184, 187190]
Have weaker differentiating potential towards osteocytes and chondrocytes
Birth-derived tissues CD29, CD44, CD73, CD90, CD105, CD146 CD14, CD34, CD45 Have relatively high proliferation rate [191193]
Produce more insulin than bone marrow MSC
Dental pulp CD29, CD44, CD90, CD105 CD14, CD34, CD45 Have odontoosteogenic properties [194196]
Locate within the dental crown
Peripheral blood CD44, CD54, CD90, CD105, CD166, HLA-ABC CD14, CD34, CD45, CD31 Manifest similar immunophenotypes and differentiation potential to those of bone marrow MSC [197199]
The volume of blood is large
Endometrium CD73, CD90, CD105, CD146 CD34, CD45 Have the potential of mesodermal lineage differentiation [197, 200, 201]
Producing high level of leukemia inhibitory factors
Skin CD44, CD73, CD90, CD105, CD166, CD29 CD34, CD45, HLA-DR Have higher proliferation rate than that of adipose MSC (202204)