Table 3.
Characteristics and complications in subgroup of neonates treated with ET.
|
Group I n = 104 |
Group II n = 39 |
Group III n = 10 |
|
|---|---|---|---|
| Number of ET(s) per neonate a | 1 (1–2) | 1 (1–2) | 1 (1–1) |
| Time to first ET ‐ hours after birth a | 6 (5–9) | 31 (15–55) | 50 (18–65) |
| Mechanical ventilation ‐ n (%) | 4 (4) | 0 (0) | 0 (0) |
| Proven sepsis as related to ET ‐ n (%) b | 6 (6) | 4 (11) | 1 (10) |
| Umbilical vein thrombosis ‐ n (%) c | 1 (1) | 0 (0) | 0 (0) |
| Leukocytopenia < 5·109/L ‐ n (%) d | 66 (63) | 27 (71) | 3 (33) |
| Thrombocytopenia < 100·109/L ‐ n (%) e | 101 (98) | 36 (97) | 10 (100) |
| 25‐49·109/L | 41 (40) | 19 (50) | 3 (30) |
| <25·109/L | 21 (20) | 5 (13) | 0 (0) |
| Neonates receiving platelet transfusion(s) ‐ n (%) | 56 (54) | 23 (59) | 3 (30) |
| Hypocalcaemia < 8·0 mg/dL ‐ n (%) | 12 (12) | 6 (15) | 0 (0) |
| Hyperkalaemia > 6·5 mEq/L ‐ n (%) | 1 (1) | 1 (3) | 0 (0) |
| Hearing screening performed ‐ n (%) | 43 (41) | 32 (82) | 8 (80) |
| Hearing screening passed ‐ n (%) f | 43 (100) | 32 (100) | 8 (100) |
| Cerebral ultrasound performed ‐ n (%) | 51 (49) | 35 (90) | 10 (100) |
| Minor IVH, grade I or II ‐ n (%) | 0 (0) | 0 (0) | 0 (0) |
| Major IVH, grade III or IV ‐ n (%) | 0 (0) | 1 (3) | 0 (0) |
| Cystic PVL ‐ n (%) | 0 (0) | 1 (3) | 0 (0) |
| Mortality ‐ n (%) | 0 (0) | 0 (0) | 0 (0) |
ET, exchange transfusion; IQR, interquartile range; IUT, intrauterine transfusion; IVH, intraventricular haemorrhage; PVL, periventricular leukomalacia; SD, standard deviation.
a
Median (IQR).
b
Sepsis defined as symptomatic infection with positive blood culture, onset later than first ET.
c
Only one neonate underwent a catheter ultrasound.
d
one missing value in group II.
e
three missing values, one in each group.
f
61 missing values in group II, seven missing values in group II, two missing values in group III.