AZD2423 |
AstraZeneca |
II |
CCR2 |
Chronic obstructive pulmonary disease (COPD) |
Inactive |
NCT01215279 |
BMS-687681 |
Bristol-Myers Squibb |
Pre |
CCR2, CCR5 |
Cancer |
Active |
(174) |
BMS-741672 |
Bristol-Myers Squibb |
II |
CCR2 |
Type II diabetes |
Inactive |
NCT00699790 |
BMS-813160 |
Bristol-Myers Squibb |
I/II |
CCR2, CCR5 |
Pancreatic cancer, Colorectal cancer, Liver cancer, NSCL |
Active |
NCT03184870; NCT04123379
|
BMS-813160 |
Bristol-Myers Squibb |
II |
CCR2, CCR5 |
Type II diabetes |
Active, Inactive |
NCT01752985 |
CCX140 |
ChemoCentryx, Vifor Pharma |
II |
CCR2 |
Type II diabetes, Fibrosis |
Active |
(175), NCT01447147. |
CCX872 |
ChemoCentryx |
I/II |
CCR2 |
Pancreatic cancer |
Active, Inactive |
NCT02345408, NCT03778879
|
Cenicriviroc |
Takeda Pharmaceuticals, Dong-A Pharma, Tobira Therapeutics (AbbVie) |
II |
CCR2, CCR5 |
HIV |
Inactive |
(176) |
Cenicriviroc |
Takeda Pharmaceuticals, Dong-A Pharma, Tobira Therapeutics (AbbVie) |
III |
CCR2, CCR5 |
NASH, HIV, COVID19 |
Active, Inactive |
NCT03028740 |
CNTX-6970 |
Centrexion Therapeutics |
I |
CCR2 |
Pain |
Active |
NCT03787004 |
INCB8696 |
Incyte |
I |
CCR2 |
MS |
Inactive |
(177) |
INCB3344 |
Incyte |
Pre |
CCR2 |
MS, RA |
Inactive |
(178) |
INCB3284 |
Incyte |
Pre |
CCR2 |
Undefined inflammation |
Inactive |
(179) |
INCB10820 |
Incyte, Pfizer |
Pre |
CCR2, CCR5 |
Autoimmune diseases |
Inactive |
(180) |
JNJ-17166864 |
Johnson & Johnson |
II |
CCR2 |
Allergic rhinitis |
Inactive |
NCT00604123 |
JNJ-27141491 |
Johnson & Johnson |
Pre |
CCR2 |
MS |
Inactive |
(181) |
JNJ-41443532 |
Johnson & Johnson |
II |
CCR2 |
Type II diabetes |
Inactive |
NCT01230749 |
MK-0812 |
Merck & Co. |
II |
CCR2 |
RA, MS |
Inactive |
NCT00239655 |
PF-04136309 |
Incyte, Pfizer |
II |
CCR2 |
Pancreatic cancer, Arthritic pain, Chronic hepatitis |
Inactive |
NCT02732938; NCT00689273; NCT01226797
|
PF-04634817 |
Pfizer |
II |
CCR2, CCR5 |
Type II diabetes |
Inactive |
NCT01712061 |
RAP-103 |
Creative Bio-Peptides |
Pre |
CCR2, CCR5, CCR8 |
Neurophathic Pain |
Active |
(182) |
RO5234444 |
Roche |
Pre |
CCR2 |
Type II diabetes |
Inactive |
(183) |
SSR150106 |
Sanofi |
II |
CCR2 |
RA |
Inactive |
NCT00545454 |
Tropifexor+Cenicriviroc |
Allergan (AbbVie), Novartis |
II |
CCR2, CCR5, FXR |
NASH |
Active |
CLJC242A2201J; NCT03517540
|
WXSH0213 |
WuXi AppTec, Zhongsheng Pharmaceuticals |
Pre |
CCR2, CCR5 |
NASH |
Active |
(184) |
Bindarit |
Angelini |
II |
CCL2 |
Type II diabetes, Atherosclerosis |
Inactive |
NCT01109212 |
NOX-E36 |
NOXXON Pharma AG |
II |
CCL2 |
Type II diabetes |
Inactive |
NCT01547897 |
NOX-E36 |
NOXXON Pharma AG |
Pre |
CCL2 |
Liver fibrosis |
Inactive |
(185) |