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(a) Representative T1-weighted MRI images of a mouse obtained before (PRE) and after (1 and 5 h) the injection of Mn@HFn-RT (50 mg/kg HFn). The arrows indicate the muscle (m) and tumor (T) regions and (b) the intensity of the bright signal quantified in the tumor region normalized against the brightness of the muscle. The values are the mean of at least three mice ± SE. *P < 0.05; ***P < 0.005 (Student’s t-test).
