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. 2021 Nov 3;9:733823. doi: 10.3389/fped.2021.733823

Table 4.

Physiological parameters that are modified for pregnancy prediction in Simcyp p-PBPK model.

List of parameters
Cardiac output
Total body weight
Total fat
Plasma volume
Red blood cell volume
Hematocrit
Serum albumin
Skin blood flow rate
Adipose blood flow rate
Renal blood flow rate
Fetoplacental unit blood flow rate
Enzyme and transporter activity