Table 1.
MIC, IC50 and LogP values of TQAS.[a]
|
Entry |
TQAS |
Chain length |
S. aureus [μg/mL] |
E. coli [μg/mL] |
IC50 [μg/mL][b] |
LogP [c] |
|---|---|---|---|---|---|---|
|
1 |
12 |
8 |
>400 |
>400 |
36 |
−5.13 |
|
2 |
13 |
12 |
300 |
>400 |
34 |
−2.07 |
|
3 |
14 |
16 |
>400 |
300 |
62 |
+1.98 |
|
4 |
15 |
8 |
>400 |
>400 |
25 |
−4.91 |
|
5 |
16 |
12 |
50 |
400 |
59 |
−1.44 |
|
6 |
17 |
16 |
300 |
200 |
67 |
+2.60 |
[a] Minimal inhibitory concentration (MIC) was calculated taking as reference the negative control as the lowest concentration which inhibits bacterial growth. All the experiments were carried out both in biological and technical triplicate. [b] IC50 values were determined on eukaryotic fibroblasts MRC‐5 cells. [c] LogP calculated using online platform Chemicalize.