TABLE 2.
Logistic Regression Analysis for the Prediction of NASH in 213 Patients With Biopsy‐Proven NAFLD
| Factor | Univariate Analysis | Multivariate Analysis | |||||
|---|---|---|---|---|---|---|---|
| OR | 95% CI | P Value | OR | 95% CI | P Value | ||
| Age (years) | Per year | 1.057 | 1.031‐1.083 | <0.05 | 1.042 | 1.008‐1.078 | <0.05 |
| Sex (M/F) | 0.8 | 0.454‐1.409 | N.S. | ||||
| Body mass index (kg/m2) | per 1 kg/m2 | 1.018 | 0.961‐1.077 | N.S. | |||
| AST (U/L) | per 10 U/L | 1.3 | 1.162‐1.454 | <0.05 | N.S. | ||
| ALT (U/L) | per 10 U/L | 1.071 | 1.009‐1.136 | <0.05 | N.S. | ||
| GGT (U/L) | per 10 U/L | 1.021 | 0.983‐1.060 | N.S. | |||
| ALP (U/L) | per 40 U/L | 1.027 | 0.925‐1.141 | N.S. | |||
| Triglyceride (mg/dL) | per 10 mg/dL | 1.019 | 0.985‐1.054 | N.S. | |||
| LDL‐C (mg/dL) | per 10 mg/dL | 0.951 | 0.873‐1.036 | N.S. | |||
| Fasting blood sugar (mg/dL) | per 10 mg/dL | 1.057 | 0.989‐1.129 | N.S. | |||
| HbA1c (%) | per 1 % | 1.219 | 0.970‐1.531 | N.S. | |||
| AFP (ng/mL) | per 1 ng/mL | 1.318 | 1.147‐1.514 | <0.05 | N.S. | ||
| Albumin (g/dL) | per 1 g/dL | 0.259 | 0.103‐0.653 | <0.05 | N.S. | ||
| Platelet count (×104/μL) | per 1X 104/μL | 0.88 | 0.837‐0.926 | <0.05 | 0.928 | 0.875‐0.984 | <0.05 |
| TSP‐2 (ng/mL) | per 1 ng/mL | 1.039 | 1.026‐1.052 | <0.05 | 1.03 | 1.016‐1.045 | <0.05 |
Abbreviations: AFP, alpha‐fetoprotein; F, female; GGT, γ‐glutamyl transpeptidase; LDL‐C, low density lipoprotein cholesterol; M, male; N.S., not significant.