TABLE 3.
Logistic Regression Analysis for the Prediction of Advanced Fibrosis (F3‐F4) in 213 Patients With Biopsy‐Proven NAFLD
| Factor | Univariate Analysis | Multivariate Analysis | |||||
|---|---|---|---|---|---|---|---|
| OR | 95% CI | P Value | OR | 95% CI | P Value | ||
| Age (years) | Per year | 1.037 | 1.010‐1.065 | <0.05 | N.S. | ||
| Sex (M/F) | 1.157 | 0.605‐2.210 | N.S. | ||||
| Body mass index (kg/m2) | per 1 kg/m2 | 1.077 | 1.011‐1.147 | <0.05 | N.S. | ||
| AST (U/L) | per 10 U/L | 1.079 | 0.976‐1.194 | N.S. | |||
| ALT (U/L) | per 10 U/L | 0.947 | 0.878‐1.021 | N.S. | |||
| GGT(U/L) | per 10 U/L | 1.009 | 0.967‐1.052 | N.S. | |||
| ALP (U/L) | per 40 U/L | 1.01 | 0.894‐1.140 | N.S. | |||
| Triglyceride (mg/dL) | per 10 mg/dL | 0.998 | 0.994‐1.002 | N.S. | |||
| LDL‐C (mg/dL) | per 10 mg/dL | 0.866 | 0.779‐0.962 | <0.05 | N.S. | ||
| Fasting blood sugar (mg/dL) per 10 mg/dL | 1.06 | 0.991‐1.134 | N.S. | ||||
| HbA1c (%) | per 1 % | 1.282 | 1.015‐1.619 | <0.05 | N.S. | ||
| AFP (ng/mL) | per 1 ng/mL | 1.257 | 1.105‐1.430 | <0.05 | N.S. | ||
| Albumin (g/dL) | per 1 g/dL | 0.198 | 0.072‐0.545 | <0.05 | N.S. | ||
| HA (ng/mL) | per 10 ng/mL | 1.094 | 1.053‐1.136 | <0.05 | N.S. | ||
| Platelet count (×104/μL) | per 1X 104/μL | 0.816 | 0.757‐0.879 | <0.05 | 0.865 | 0.795‐0.940 | <0.05 |
| TSP‐2 (ng/mL) | per 1 ng/mL | 1.043 | 1.030‐1.057 | <0.05 | 1.037 | 1.020‐1.055 | <0.05 |
Abbreviations: F, female; GGT, γ‐glutamyl transpeptidase; LDL‐C, low density lipoprotein cholesterol; M, male; N.S., not significant.