TABLE 1.
Protein profiling summary. The top 10 proteins upregulated in Fn14-low and Fn14-high rat tumors compared to normal rat brain as determined using R&D Systems Rat XL Cytokine Array Kit are listed. Proteins that are specifically overexpressed in the Fn14-high tumors compared to both normal brain and Fn14-low tumors are written in bold type
Normal brain vs. Fn14-low tumor |
Normal brain vs. Fn14-high tumor |
||
---|---|---|---|
Protein | Fold-increase | Protein | Fold-increase |
Lipocalin-2 | 4.6 | PDGF-B | 26.4 |
IGFBP-3 | 2.5 | PAI-1 | 22.9 |
RBP4 | 1.6 | IGFBP-3 | 10.4 |
IGFBP-6 | 1.6 | IGFBP-5 | 8.8 |
Galectin-3 | 1.3 | Lipocalin-2 | 8.7 |
Adiponectin | 0.8 | Osteopontin | 8.6 |
Fetuin-A | 0.7 | Adiponectin | 4.9 |
IGFBP-2 | 0.6 | IGFBP-2 | 4.0 |
RGM-A | 0.5 | Galectin-3 | 3.0 |
Osteoprotegerin | 0.4 | Osteoprotegerin | 1.2 |