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. Author manuscript; available in PMC: 2021 Nov 17.
Published in final edited form as: Glia. 2021 May 15;69(9):2199–2214. doi: 10.1002/glia.24018

TABLE 1.

Protein profiling summary. The top 10 proteins upregulated in Fn14-low and Fn14-high rat tumors compared to normal rat brain as determined using R&D Systems Rat XL Cytokine Array Kit are listed. Proteins that are specifically overexpressed in the Fn14-high tumors compared to both normal brain and Fn14-low tumors are written in bold type

Normal brain vs.
Fn14-low tumor
Normal brain vs.
Fn14-high tumor
Protein Fold-increase Protein Fold-increase
Lipocalin-2 4.6 PDGF-B 26.4
IGFBP-3 2.5 PAI-1 22.9
RBP4 1.6 IGFBP-3 10.4
IGFBP-6 1.6 IGFBP-5 8.8
Galectin-3 1.3 Lipocalin-2 8.7
Adiponectin 0.8 Osteopontin 8.6
Fetuin-A 0.7 Adiponectin 4.9
IGFBP-2 0.6 IGFBP-2 4.0
RGM-A 0.5 Galectin-3 3.0
Osteoprotegerin 0.4 Osteoprotegerin 1.2