TABLE 1.

Statistical analysis of the trabecular bone response in wild‐type mice

	Pearson's correlation		Linear regression of the slope
Category	r 2	p	Slope	95% CI
Gender
Female (n = 44)	0.8990	<0.0001	1.031	0.8746 to 1.1870
Male (n = 40)	0.7698	<0.0001	1.808	1.3160 to 2.3010
Both (n = 11)	0.3470	0.2957	0.748	−0.7763 to 2.2720
Bone site
Tibia (n = 15)	0.8631	<0.0001	1.194	0.9090 to 1.4790
Femur (n = 63)	0.5204	<0.0001	1.690	1.2750 to 2.1050
Vertebrae (n = 21)	0.1462	0.0872	0.620	−0.0996 to 1.3400
Age at start of treatment
0–2 weeks (n = 12)	0.4261	0.0214	0.988	0.1802 to 1.7970
4–8 weeks (n = 22)	0.3150	0.0066	0.752	0.2348 to 1.2690
9–10 weeks (n = 23)	0.6942	<0.0001	0.950	0.6640 to 1.2360
11–12 weeks (n = 25)	0.7071	<0.0001	1.530	1.1050 to 1.9540
>12 weeks (n = 22)	0.6239	<0.0001	2.031	1.2950 to 2.7670
Days per week of treatment
5–5.5 (n = 35)	0.8758	<0.0001	1.250	1.0060 to 1.4940
7 (n = 66)	0.6487	<0.0001	1.3178	0.9320 to 1.7010
Treatment duration
<4 weeks (n = 23)	0.6880	<0.0001	1.347	0.9357 to 1.7590
4 weeks (n = 48)	0.3858	<0.0001	0.885	0.5335 to 1.2016
5–6 weeks (n = 22)	0.6749	<0.0001	2.459	1.6630 to 3.2550
7–12 weeks (n = 12)	0.6503	0.0015	0.790	0.3814 to 1.1970
Treatment dose (μg/kg/day)
≦30 (n = 19)	0.6201	<0.0001	2.176	1.3050 to 3.0480
40 (n = 19)	0.6799	<0.0001	1.565	1.0150 to 2.1140
50–60 (n = 13)	0.3717	0.0269	1.135	0.1559 to 2.1150
80 (n = 44)	0.4488	<0.0001	0.919	0.6021 to 1.2370
90–160 (n = 10)	0.9454	<0.0001	1.001	0.8050 to 1.1970

Notes: Data was pooled to analyze Pearson's correlation of the trabecular response of wild‐type mice to vehicle or iPTH. The r ² and p value are reported from this analysis. The slope and 95% CI of the linear regression of the slope is also reported.

Abbreviations: CI, confidence interval; iPTH, intermittent parathyroid hormone.