Table 3.
Changes in cardiovascular risk factors after 3 months
| Intervention group at baseline | Intervention group after 3 months | Intervention group mean difference over time (p value) | Control group baseline | Control group after 3 months | Control group mean difference over time (p value) | Mean difference of change between IG and CG (p value) | |
|---|---|---|---|---|---|---|---|
| Systolic blood pressure (mmHg)† | 138.47 (1.4) | 135.27 (1.76) | − 3.2 (0.039)* | 139.38 (2.13) | 137.66 (1.64) | − 1.72 (0.366) | − 1.48 (0.543) |
| Diastolic blood pressure (mmHg)† | 89.6 (1.04) | 86.63 (1.16) | − 2.96 (0.020)* | 86.49 (1.35) | 86.09 (1.38) | − 0.4 (0.777) | − 2.56 (0.180) |
| Total cholesterol (mmol/L)† | 5.76 (0.12) | 5.67 (0.14) | − 0.1 (0.344) | 5.38 (0.13) | 5.27 (0.15) | − 0.11 (0.280) | + 0.01 (0.924) |
| BMI (kg/m2)† | 31.59 (0.63) | 31.59 (0.66) | + 0.01 (0.967) | 30.09 (0.78) | 30.08 (0.79) | − 0.01(0.976) | + 0.01 (0.962) |
| Waist (cm)† | 107.52 (1.6) | 107.44 (1.62) | − 0.08 (0.852) | 103.23 (1.98) | 103.66 (2.03) | + 0.43 (0.473) | − 0.51 (0.475) |
| Cigarettes per day (total number)†† | 16.86 (1.58) | 13.04 (1.46) | − 3.82 (0.004)* | 15.05 (1.76) | 17.27 (1.99) | + 2.23 (0.085) | − 6.05 (0.001)* |
| 10-year stroke or heart attack risk from decision aid(percentage) | 8.48 (0.94) | 7.83 (0.97) | − 0.65 (0.182) | 7.96 (1.43) | 7.89 (1.51) | − 0.08 (0.883) | − 0.57 (0.429) |
| QRISK-lifetime cardiovascular risk (percentage) | 61.73 (1.5) | 61.35 (1.6) | − 0.38 (0.571) | 62.38 (2) | 61.7 (2) | − 0.68 (0.400) | + 0.3 (0.773) |
Continuous variables are presented as mean and standard error of mean (SE MEAN), unless indicated as p value
BMI—body mass index kg/m2; CG—Control Group; IG—Intervention Group
*p values under 0.05 are considered as significant and tagged with an asterisk and bold
†IG n = 35; CG n = 24 (with multiple imputation regression method)
††Including patients who started or quit smoking during the follow-up period; IG n = 21; CG n = 22