Table 4.
Changes in Cardiovascular Risk Factors of Patients with Hypertension Grade 2 after 3 months
| Intervention group at baseline | Intervention group after 3 months | Intervention group mean difference over time (p value) | Control group baseline | Control group after 3 months | Control group mean difference over time (p value) | Mean difference of change between IG and CG (p value) | |
|---|---|---|---|---|---|---|---|
| Systolic blood pressure (mmHg)† | 140.77 (1.79) | 134.77 (2.42) | − 6 (0.021)* | 135.42 (2.92) | 137.27 (2.37) | + 1.86(0.471) | − 7.86 (0.038)* |
| Diastolic blood pressure (mmHg)† | 91.57 (1.73) | 87.39 (1.65) | − 4.18 (0.056) | 88.08 (2.06) | 88.77 (1.99) | + 0.69 (0.730) | − 4.87 (0.119) |
| Total cholesterol (mmol/L)† | 5.69 (0.19) | 5.59 (0.23) | − 0.09 (0.540) | 5.48 (0.21) | 5.39 (0.23) | − 0.09 (0.594) | − 0.01 (0.985) |
| BMI (kg/m2)† | 32.84 (1.09) | 32.99 (1.15) | + 0.15 (0.627) | 32.2 (1.2) | 32.15 (1.24) | − 0.05 (0.792) | + 0.2 (0.617) |
| Waist (cm)† | 110.49 (2.7) | 110.17 (2.81) | − 0.31 (0.579) | 108.58 (2.87) | 108.65 (3.08) | + 0.06 (0.947) | − 0.38 (0.721) |
| Cigarettes per day (total number)†† | 17.67 (2.58 | 14.2 (2.18) | − 3.47 (0.069) | 13.7 (2.03) | 15 (1.49) | + 1.3 (0.471) | − 4.77 (0.073) |
| 10-year stroke or heart attack risk from decision aid(percentage) | 9.59 (1.53) | 8.7 (1.49) | − 0.89 (0.214) | 7.87 (1.91) | 8.13 (2.09) | + 0.26 (0.753) | − 1.15 (0.287) |
| QRISK-lifetime cardiovascular risk (percentage) | 62.82 (2.24) | 62.1 (2.42) | − 0.71 (0.445) | 65.42 (2.7) | 65.44 (2.9) | + 0.02 (0.985) | − 0.69 (0.585) |
Continuous variables are presented as mean and standard error of mean (SE MEAN)
BMI—body mass index kg/m2; CG—Control Group; IG—Intervention Group
*p values under 0.05 are considered as significant and tagged with an asterisk
†IG n = 35; CG n = 24 (with multiple imputation regression method)
††including patients who started or quit smoking during the follow-up period; IG n = 12; CG n = 10