FIGURE 2.

Post hoc Tukey test results of the different polygenic risk scores (PRSs) associated with the CD4⁺/CD8⁺ ratio and other T cell subsets. Numbers on the x‐axis correspond to the different quartiles of the multiple sclerosis (MS)‐PRS. Based on increasing MS‐PRS, the participants were divided into four quartiles of similar sample size. (a) Association between total CD8⁺ cells and the quartiles of the MS‐PRS (P _T < 0.005). (b) Association between naive CD8⁺ cells and the quartiles of the MS‐PRS (P _T < 0.005). (c) Association between the CD4⁺/CD8⁺ ratio and the quartiles of the MS‐PRS (P _T < 0.005). (d) Association between the CD4⁺/CD8⁺ ratio and the quartiles of the MS‐PRS (P _T < 5 × 10⁻⁸)