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Normalized inhibition (Inorm ) of test compounds with paracyclophane scaffold. The reduced ion flux across the oocyte membrane was measured at a concentration of 10 μM of the test compounds after activation with 10 μM (S)‐glutamate and 10 μM glycine. The inhibition obtained by TCN‐201 (1, 10 μM) was set to 100 % and the inhibition of the test compounds (10 μM) was normalized to this activity (in %). The activity of each compound was measured with three independent oocytes (n=3).
