Table 2.
Patients | n = 20 |
---|---|
Months after COVID-19 | 2 (1.4–3.5) |
sCr at biopsy, mg/dL | 1.5 (1.4–2.4) |
Δ sCr, basal-biopsy, mg/dL | 0.7 (0.2–1.3) |
Δ sCr, COVID diagnosis-biopsy, mg/dL | − 0.28 (− 1.1 to + 0.02) |
Persistent kidney dysfunction | 7 (35) |
Tacrolimus, ng/ml | 6.4 (5.2–7.6) |
PRA I, % | 4 (0–17) |
PRA II, % | 10 (2–19) |
De novo DSA | 11 (55) |
Class I | 2 (10) |
Class II | 6 (30) |
Class I & II | 3 (15) |
Kidney biopsy | |
Glomeruli | 21 (10–27) |
Diagnosis | |
No major abnormalities | 6 (30) |
Borderline for acute TCMR | 2 (10) |
Chronic active TCMR | 1 (5) |
Active ABMR | 3 (15) |
Mixed ABMR/TCMR | 4 (20) |
Chronic active ABMR | 4 (20) |
Values stated in n (%), median (25–75%) or mean ± sd
Δ delta, ABMR antibody mediated rejection, COVID-19 coronavirus disease-19, sCr serum creatinine, DSA donor-specific antibodies, MMF mycophenolate mofetil, PRA panel reactive antibody, TCMR T-cell mediated rejection