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. 2021 Nov 17;14:159. doi: 10.1186/s13048-021-00913-x

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — The effects of CXCL14 knockdown or overexpression on Wnt/β-catenin signaling-related markers. A Representative images of immunohistochemical staining of β-catenin in surgical specimens from OC tissues and non-tumor ovarian tissues (original magnification, × 100). B Correlation study of CXCL14 and β-catenin in OC tissues. Pearson correlation coefficient were used for statistical analysis of the correlation between CXCL14 and β-catenin. C Western blotting shows that overexpressing CXCL14 in OC cells increased the nuclear accumulation of β-catenin, respectively. ^**P < 0.01 compared with vector. D-E Following CXCL14 shRNA or overexpression treatment, qRT-PCR detection of the mRNA levels (cyclin D1, MMP-7, Axin2) in OC cells. ^**P < 0.01. F-G Following CXCL14 shRNA or overexpression treatment, western blotting detection of the protein expressions of cyclin D1, MMP-7 and Axin2 in OC cells. ^**P < 0.01 compared with sh-NC or vector