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. Author manuscript; available in PMC: 2021 Nov 17.
Published in final edited form as: Nat Microbiol. 2021 Apr 19;6(6):731–745. doi: 10.1038/s41564-021-00890-3

Extended Data Fig. 3. Related to Figure 2.

Extended Data Fig. 3

A, B: Binding curves of CC30 (A) and CC8 (B) LukAB toxins to CD11b I-domain. The association and dissociation kinetics of LukAB with the I-domain coated sensor are represented in blue. Toxin concentrations are 400nM, 200nM, and 100nM for CC30 LukAB, or 125nM, 62.5nM, and 31.3nM for CC8 LukAB. Red curves show the best global fit using a 1:1 binding model.