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. 2021 May 28;30(11):1662–1674. doi: 10.1111/exd.14390

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© 2021 The Authors. Experimental Dermatology published by John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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FIB‐116 inhibits the proliferative effect and pro‐inflammatory response of TSLP in cultured keratinocytes. (A) Experimental design for induction of primary murine keratinocytes with recombinant TSLP and treatment with amygdalin analogue in vitro. (B) Representative immunofluorescence images for EdU (green) of primary murine keratinocytes in the different treatments. Nuclei (Dapi) in red. (C) Percentage of EdU+keratinocytes after treating with recombinant TSLP and Amygdalin analogue. Statistical significance *p < 0.05 (t‐student two‐tailed test). (D‐G) Gene expression of Cyca2, Il10, Il23a and Il6 in TSLP‐induced keratinocytes treated with amygdalin analogue. Statistical significance *p < 0.05 (t‐student two‐tailed test)