Fig. 6.

Relationship between circulating microRNAs and human placental lactogen (hPL) in maternal serum. Correlation between serum miRNA expression measured by qPCR and hPL a hormone marker of placental dysfunction detected by ELISA for A miR-28-5p, B miR-29c-3p, C miR-301a-3p, D miR-378a-3p, E miR-409-3p, F miR-454-3p and G miR-526b-5p. Positive correlations with hPL were detected for B miR-29c-3p (r² 0.3519, p < 0.05) and F miR-454-3p (r² 0.449, p < 0.001). Individual data points shown (n = 34–56), line represents the median. Spearman rank correlations