Fig. 3.
HG- and RGI-rich pectins exhibited synergistic effect on cell migration. (A) The synergistic effect of WGPA-3HG and RGI-high or RGI-low on L-929 cell migration in scratching assay. Cells treated with either 1.0 mg/ml of RGI-high, RGI-low, WGPA-3HG, or 1.0 mg/ml of mixture comprising equal amount of RGI-high (or RGI-low) and WGPA-3HG were tested. (B) The synergistic effect of WGPA-3HG and RGI-high on L-929 cell migration in transwell assay. Cells treated with increasing concentrations of either RGI-high, or WGPA-3HG, or the mixture comprising equal proportion of RGI-high and WGPA-3HG were tested. Values were means ± SD from three experiments in A and two experiments in B, * p < 0.001, # 0.001 < p < 0.01.