Table 3.

Comparison of Adverse Events in the Entire EIE Patient Cohort Treated With Ampicillin-Ceftriaxone or Ampicillin-Gentamicin

	AC (n = 100)	AG (n = 90)	P Value
Rash	1	1
Ototoxicity	0	8
Leukopenia	1	4
Antibiotic associated diarrhea	4	7
Clostridioides difficile colitis	8	5
Acute kidney injury	6	13
Other	5	1
Total number of adverse eventsa	25	39	.0091

Abbreviations: AC, ampicillin-ceftriaxone; AG, ampicillin-gentamicin; EIE, enterococcal infective endocarditis.

^aSeveral patients had multiple documented adverse events.