Table 1.
Information on global CV-A6 evolutionary lineages. Mainland China is indicated as bold characters.
| Genotype/subtype | Lineage | n | Nucleotide mean distances (%) | Isolated countries/regions | Isolated years | Occurrence time | Recombination breakpoints position (within subtype) |
|---|---|---|---|---|---|---|---|
| Subtype D1 | B | 8 | 4.2 | Australia; Japan | 1999–2006 | 1996–1999 | Original lineage of subtype D1 (query) |
| E | 4 | 1.2 | Taiwan of China | 2007 | 1997–2007 | End of 2C | |
| Subtype D2 | C | 10 | 4.4 | Mainland China; Japan | 2005–2012 | 1996–2005 | Original lineage of Subtype D2 (query) |
| D | 4 | 2.8 | Mainland China | 2011–2013 | 2008–2011 | Middle of 3Dpol | |
| K1 | 2 | 1.7 | Mainland China | 2013 | 2008–2013 | Beginning of 2C | |
| Subtype D3 | A | 59 | 4.8 | Australia; Mainland China; Germany; Denmark; Finland; Hong Kong of China; India; Japan; Thailand; Taiwan of China; United Kingdom; United State; Vietnam | 2008–2018 | 2003–2008 | Original lineage of subtype D3 (query) |
| F | 8 | 1.6 | Germany; Spain; Thailand; United Kingdom | 2012–2014 | 2007–2012 | Beginning of 2B | |
| G | 5 | 1.9 | Denmark; United Kingdom | 2011–2014 | 2003–2011 | Original lineage of subtype D3 | |
| H | 6 | 0.9 | Denmark; Spain; United Kingdom | 2013–2014 | 2011–2013 | Beginning of 2C | |
| J | 13 | 2.3 | Mainland China | 2012–2017 | 2010–2012 | End of 2A | |
| K2 | 2 | 0.5 | Mainland China | 2013 | 2010–2013 | End of 2C | |
| L | 12 | 2.6 | Mainland China; Hong Kong of China | 2014–2018 | 2013–2014 | Middle of 3Dpol | |
| M | 1 | NA | Hong Kong of China | 2015 | 2012–2015 | End of 3C | |
| N | 4 | 2 | Australia | 2016–2017 | 2011–2016 | Middle of 2C | |
| Genotype E | O | 1 | NA | Madagascar | 2011 | 2004–2011 | NA |
| P | 1 | NA | Madagascar | 2011 | 2004–2011 | NA | |
| Genotype A | I(prototype) | 1 | NA | United State | 1949 | 1930–1949 | NA |