Table 1.

Comparison of shape component magnitudes in systole, diastole, and looking at global minima and maxima across one cardiac cycle

	Shape component
Frame	0	1	2	3	4	5	6	7	8	9	10
P values for shape component magnitude comparisons
Control versus PH
Systole	6.93 × 10−3	1.41 × 10−3	1.53 × 10−5a	5.97 × 10−7a	2.47 × 10−4	3.60 × 10−5a	7.72 × 10−6a	1.75 × 10−5a	1.30 × 10−4	8.32 × 10−5a	5.39 × 10−5a
Minimum across cycle	6.93 × 10−3	1.63 × 10−1	5.42 × 10−5a	2.26 × 10−5a	7.86 × 10−4	2.57 × 10−2	1.71 × 10−3	1.57 × 10−4	3.61 × 10−2	5.21 × 10−4	1.57 × 10−3
Diastole	1.88 × 10−3	3.39 × 10−1	3.73 × 10−4	1.89 × 10−4	3.16 × 10−4	5.74 × 10−3	1.17 × 10−3	1.26 × 10−4	3.62 × 10−2	9.95 × 10−5a	1.08 × 10−2
Maximum across cycle	1.88 × 10−3	9.61 × 10−3	2.86 × 10−5a	8.52 × 10−7a	2.10 × 10−4	4.63 × 10−5a	1.16 × 10−5a	3.88 × 10−6a	1.48 × 10−4	1.75 × 10−5a	4.64 × 10−5a
P values for shape component magnitude comparisons
TR velocity < 3.6 m/s
Control versus PH
Systole	3.52 × 10−2b	1.25 × 10−1	1.17 × 10−2b	4.10 × 10−2b	2.29 × 10−2b	1.66 × 10−2b	5.91 × 10−2	2.17 × 10−2b	1.99 × 10−1	1.01 × 10−1	2.62 × 10−2b
Minimum across cycle	3.52 × 10−2b	9.85 × 10−1	3.78 × 10−2b	4.74 × 10−2b	2.60 × 10−2b	1.99 × 10−1	4.98 × 10−1	1.01 × 10−1	2.38 × 10−1	1.81 × 10−2b	1.68 × 10−1
Diastole	5.44 × 10−2	6.09 × 10−1	1.60 × 10−1	1.72 × 10−1	1.78 × 10−2b	2.82 × 10−1	3.14 × 10−1	1.43 × 10−1	2.65 × 10−1	2.91 × 10−2b	6.62 × 10−1
Maximum across cycle	6.44 × 10−1	3.46 × 10−1	5.13 × 10−2	5.14 × 10−2	8.95 × 10−2	9.01 × 10−2	9.76 × 10−2	4.00 × 10−2b	9.56 × 10−2	3.55 × 10−2b	4.47 × 10−2b

^ap values < 0.0001 using a two tailed, paired t-test. Low TR velocity cohort includes only age/sex matched pairs with a TR velocity less than 3.60 m/s (17 subject pairs).

^bp values < 0.05 using a two tailed, paired t-test.