FIG 3.

Activity of bedaquiline (BDQ) alone (A), BDQ plus meropenem (MEM) (B), BDQ plus MmpL3 inhibitor (MPL) (C), and BDQ plus clarithromycin (CLR) (D) against M. abscessus ATCC 19977 WT in CAMHB with 0.05% Tween 80. The number after each drug abbreviation represents the concentration in μg/ml. MPL is N-4S-methylcyclohexyl-4,6-dimethyl-1H-indole-2-carboxamide. The bacteria in the no-drug control overgrew and clumped after Day 3, precluding CFU quantification. CFU values are provided in Table S5.