FIG 7.

Analysis of cryptococcal growth in the presence of subinhibitory amphotericin B and MAbs DD11 or CC5. C. neoformans cells were incubated in the absence or presence of MAbs, both at concentrations varying from 0 to 12.5 μg/ml. Alternatively, fungal cells were cultivated in the presence of a subinhibitory concentration of amphotericin B (AmB; 0.1 μg/ml) alone (no MAb [0 μg/ml]) or in combination with the MAbs. The combination of the MAbs with subinhibitory amphotericin B resulted in inhibition of fungal growth. The results illustrate a representative experiment, with three independent replicates producing similar results.