Table 1.
Effect of fenofibrate on serum lipid profile, serum TBAR, renal GSH, serum nitrite/nitrate (μM) and renal tissue nitrite levels
| Assessment | Normal Control | Nicotine | Fenofibrate treated Group |
|---|---|---|---|
| Serum cholesterol (mg/dl) | 70.12±6.6 | 174.25±9.1a | 98.4±3.01b |
| Triglycerides (mg/dl) | 80.2±6.6 | 145±10.1a | 95.8±7.2b |
| High density lipoprotein (mg/dl) | 38.6±04 | 30.1±0.8a | 36±0.7b |
| Serum TBAR (μM) | 3.5±0.3 | 8.3±0.26a | 6.75±0.56b |
| Renal GSH (μM/g wet weight of renal tissue) | 0.75±0.07 | 0.25±0.02a | 0.52±0.02b |
| Serum nitrite/nitrate (μM) | 13±0.29 | 7±0.5a | 11.3±0.3b |
| Tissue nitrite/nitrate (μM/mg of protein) | 17±0.4 | 6±0.3a | 13±0 0.35b |
All values are represented as mean±SD. aP<0.05 vs. normal control. bP<0.05 vs nicotine control