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. 2021 Nov 3;11:729887. doi: 10.3389/fonc.2021.729887

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Copyright © 2021 Li, Deng, Pang, Huang, Zhang, Zhu, Chen and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The nine-regulator-mediated m⁵C methylation modification patterns. (A) PCA analysis based on nine m⁵C regulators. (B, C) Consensus clustering was adopted for identifying the different m⁵C modification patterns. (D) The expression levels of 9 m⁵C regulators in different m⁵C modification patterns. (E) Survival analysis of the three subtypes. ***statistical significance.