Table 2.
Neurodevelopmental outcome in infants (<2 years old) born with esophageal atresia
Age (months) | Author, year | No. of patients ( n ) | Test method | Outcome measure | Test result | Conclusion |
---|---|---|---|---|---|---|
6 | Gischler*22 Netherlands, 2009 |
13 | BSID-I | Motor | 98.5 (89.3–107.7)A | Normal |
Cognition | 91.5 (79.0–104.0) | |||||
Francesca34 Italy, 2020 |
82 | Bayley-3 | Motor | 98.4 ± 12.8B | Normal | |
Cognition | 93.9 ± 10.4 | |||||
12 | Gischler22 Netherlands, 2009 |
13 | BSID-I | Motor | 98.8 (86.8–110.8)A | Normal |
Cognition | 97.2 (77.0–117.5) | |||||
Faugli36 Norway, 2009 |
36 | BSID-II | Motor | 97 (56–121)C | Normal | |
Cognition | 103 (71–118) | |||||
Walker35 Australia, 2013 |
31 | Bayley-3 | Fine motor | 9.16D | Expressive language impaired (P < 0.05), other scales normal | |
Gross motor | 8.37 | |||||
Cognition | 11.00 | |||||
Receptive language | 10.23 | |||||
Expressive language | 9.03 | |||||
Francesca34 Italy, 2020 |
59 | Bayley-3 | Motor | 93.4 ± 10.3B | Normal | |
Cognition | 103.3 ± 9.1 | |||||
Giúdici23 Argentina, 2016 |
21 | CAT/CLAMS | Visomotor & receptive and expressive language skills | Normal in n = 16 (76%) Abnormal n = 5 (24%) |
Significantly lower than normal | |
Batta37 Australia, 2020 |
27 | GMDS-II | Neurodevelopment | 93 (85–100)E | Normal | |
18 | Gischler22 Netherlands, 2009 |
13 | BSID-I | Motor | 99.2 (83.0–115.4)A | Normal |
Cognition | 99.6 (87.5–111.6) | |||||
Cognition | 93 (78–113) |
BOS, Bayley Ontwikkelings Schalen (Dutch version of BSID-I); BSID, Bayley Scales of Infant and Toddler Development; CAT/CLAMS, Capute Scale Clinical Adaptive Test/Clinical Auditory Milestone Scale; GMDS, Griffiths Mental Development Scales; US, United States.
AMean (95% confidence interval).
BMean ± standard deviation.
CMean (range).
DMean.
EMedian (IQR).