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. 2021 Aug 10;34(11):doab054. doi: 10.1093/dote/doab054

Table 2.

Neurodevelopmental outcome in infants (<2 years old) born with esophageal atresia

Age (months) Author, year No. of patients ( n ) Test method Outcome measure Test result Conclusion
6 Gischler*22
Netherlands, 2009
13 BSID-I Motor 98.5 (89.3–107.7)A Normal
Cognition 91.5 (79.0–104.0)
Francesca34
Italy, 2020
82 Bayley-3 Motor 98.4 ± 12.8B Normal
Cognition 93.9 ± 10.4
12 Gischler22
Netherlands, 2009
13 BSID-I Motor 98.8 (86.8–110.8)A Normal
Cognition 97.2 (77.0–117.5)
Faugli36
Norway, 2009
36 BSID-II Motor 97 (56–121)C Normal
Cognition 103 (71–118)
Walker35
Australia, 2013
31 Bayley-3 Fine motor 9.16D Expressive language impaired (P < 0.05), other scales normal
Gross motor 8.37
Cognition 11.00
Receptive language 10.23
Expressive language 9.03
Francesca34
Italy, 2020
59 Bayley-3 Motor 93.4 ± 10.3B Normal
Cognition 103.3 ± 9.1
Giúdici23
Argentina, 2016
21 CAT/CLAMS Visomotor & receptive and expressive language skills Normal in n = 16 (76%)
Abnormal n = 5 (24%)
Significantly lower than normal
Batta37
Australia, 2020
27 GMDS-II Neurodevelopment 93 (85–100)E Normal
18 Gischler22
Netherlands, 2009
13 BSID-I Motor 99.2 (83.0–115.4)A Normal
Cognition 99.6 (87.5–111.6)
Cognition 93 (78–113)

BOS, Bayley Ontwikkelings Schalen (Dutch version of BSID-I); BSID, Bayley Scales of Infant and Toddler Development; CAT/CLAMS, Capute Scale Clinical Adaptive Test/Clinical Auditory Milestone Scale; GMDS, Griffiths Mental Development Scales; US, United States.

AMean (95% confidence interval).

BMean ± standard deviation.

CMean (range).

DMean.

EMedian (IQR).