Skip to main content
. 2021 Nov 17;7(47):eabg9551. doi: 10.1126/sciadv.abg9551

Fig. 5. Gene essentiality screening identifies potential vulnerabilities in MM-PSN subgroups.

Fig. 5.

Selected genes that are considered essential for cell survival according to the CRISPR-Cas9 screening data retrieved from DepMap. Lower CERES scores indicate higher essentiality. A green star symbol in the heatmap header indicates that the gene was identified based on cell lines that were also specifically matched to the corresponding subgroups. For the other subgroups, genes were identified using all the available MM cell lines in DepMap.