Table 2. Clinical outcomes comparing between NSTEMI and STEMI within and beyond 6 months.
| Endpoints | NSTEMI | STEMI | Crude HR | P value | Adjusted HR | P value | ||
|---|---|---|---|---|---|---|---|---|
| N of patients with event | (95%CI) | (95%CI) | ||||||
| (Cumulative incidence) | ||||||||
| All-cause death | ||||||||
| Within 6 months | 120 | (7.6%) | 402 | (8.8%) | 0.86(0.70–1.05) | 0.13 | 0.83(0.67–1.03) | 0.09 |
| Beyond 6 months | 321 | (18.6%) | 694 | (13.9%) | 1.37(1.20–1.56) | <0.001 | 1.04(0.90–1.20) | 0.59 |
| Cardiovascular death | ||||||||
| Within 6 months | 101 | (6.4%) | 362 | (7.9%) | 0.80(0.64–1.00) | 0.047 | 0.82(0.65–1.03) | 0.09 |
| Beyond 6 months | 151 | (9.5%) | 329 | (7.2%) | 1.35(1.12–1.64) | 0.002 | 0.94(0.77–1.15) | 0.55 |
| Non-cardiovascular death | ||||||||
| Within 6 months | 19 | (1.3%) | 40 | (0.9%) | 1.35(0.78–2.34) | 0.28 | - | - |
| Beyond 6 months | 170 | (10.0%) | 365 | (7.2%) | 1.38(1.15–1.66) | 0.001 | 1.13(0.93–1.37) | 0.21 |
| Myocardial infarction | ||||||||
| Within 6 months | 41 | (2.7%) | 132 | (3.0%) | 0.89(0.62–1.26) | 0.501 | 0.75(0.52–1.08) | 0.12 |
| Beyond 6 months | 102 | (6.5%) | 174 | (3.8%) | 1.76(1.38–2.25) | <0.001 | 1.38(1.06–1.78) | 0.02 |
| Stroke | ||||||||
| Within 6 months | 37 | (2.4%) | 120 | (2.7%) | 0.88(0.61–1.28) | 0.51 | 0.71(0.48–1.04) | 0.08 |
| Beyond 6 months | 80 | (5.3%) | 224 | (4.9%) | 1.05(0.81–1.35) | 0.71 | 0.83(0.63–1.08) | 0.16 |
| Hospitalization for heart failure | ||||||||
| Within 6 months | 54 | (3.6%) | 145 | (3.4%) | 1.06(0.77–1.45) | 0.72 | 0.75(0.54–1.04) | 0.08 |
| Beyond 6 months | 156 | (9.7%) | 291 | (6.4%) | 1.58(1.30–1.92) | <0.001 | 1.15(0.94–1.42) | 0.19 |
| Major bleeding | ||||||||
| Within 6 months | 191 | (12.1%) | 638 | (14.1%) | 0.85(0.72–1.00) | 0.052 | 0.81(0.68–0.96) | 0.01 |
| Beyond 6 months | 177 | (12.9%) | 359 | (8.6%) | 1.43(1.20–1.71) | <0.001 | 1.16(0.96–1.40) | 0.13 |
| Target vessel revascularization | ||||||||
| Within 6 months | 107 | (7.1%) | 305 | (7.1%) | 1.00(0.80–1.25) | 0.99 | 0.84(0.67–1.06) | 0.14 |
| Beyond 6 months | 252 | (18.7%) | 610 | (15.4%) | 1.21(1.05–1.4) | 0.01 | 1.16(0.99–1.35) | 0.07 |
| Any coronary revascularization | ||||||||
| Within 6 months | 139 | (9.3%) | 404 | (9.4%) | 0.98(0.81–1.19) | 0.84 | 0.84(0.69–1.03) | 0.09 |
| Beyond 6 months | 350 | (26.5%) | 853 | (22.2%) | 1.21(1.07–1.37) | 0.003 | 1.14(1.00–1.30) | 0.053 |
Number of patients with event beyond 6 months was counted until the end of follow-up.
Cumulative incidence was presented at 6-month for within 6 months, and at 5-year for beyond 6 months.
The risk of NSTEMI relative to STEMI was expressed as HR with 95%CI. The risk-adjusting variables in the multivariate Cox proportional hazard models were indicated in Table 1.
STEMI = ST-segment elevation myocardial infarction; NSTEMI = Non ST-segment elevation myocardial infarction; HR = hazard ratio; CI = confidence interval.