Genetic reagent (Mus musculus) |
C57B/L6-Cdh23753A>G
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Derived from Lentz et al., 2010
|
C57BL6 |
Lentz et al. Dev. Neurobiol (2010) |
Genetic reagent (Mus musculus) |
019146 - B6.129-Tmc1tm1.1Ajg/J |
Available from Jackson Lab, obtained initially from Dr A Griffith (NIH/NIDCD) |
Tmc1 Targeted (Reporter, Null/Knockout) |
Kurima et al. Nat Genet. (2002) |
Genetic reagent (Mus musculus) |
019147 - B6.129-Tmc2tm1.1Ajg/J |
Available from Jackson Lab, obtained initially from Dr A Griffith (NIH/NIDCD) |
Tmc2 Targeted (Reporter, Null/Knockout) |
Kawashima et al. J Clin Invest (2011) |
Genetic reagent (Mus musculus) |
003929 - BXA4/Pgn-Tmiesr-J/J |
Available from Jax C57BL/6-Tmiesr (‘spinner’) mice |
Spontaneous mutation in Tmie |
Stock No. 000543Mitchem et al. Hum Mol Genet. (2002) |
Genetic reagent (Mus musculus) |
Tmc1Bth
|
Tmc1Bth/Bth mice were obtained from M Hrabé de Angelis and H Fuchs, Institute of Experimental Genetics, Neuherberg, Germany |
Point mutation at residue 412 (M412K) |
Vreugde et al. Nat Genet. (2002) |
Antibody |
Anti-CtBP2 (Mouse IgG1 monoclonal) |
BD Transduction Laboratories |
Cat #: 612044 |
Primary antibody, IF (1:200) |
Antibody |
Anti-GluA2 (Mouse IgG2a monoclonal) |
Millipore Sigma |
Cat #: MABN1189 |
Primary antibody, IF (1:2000) |
Antibody |
Anti-MyosinVIIA (Rabbit polyclonal) |
Proteus Biosciences |
Cat #: 25–6790 |
Primary antibody, IF (1:200) |
Antibody |
Anti-Rabbit Alexa Fluor 647 (Donkey polyclonal) |
Thermo Fisher Scientific |
Cat #: A-31573 |
Secondary antibody, IF (1:200) |
Antibody |
Anti-Mouse IgG2a Alexa Fluor 488 (Goat polyclonal) |
Thermo Fisher Scientific |
Cat #: A-21131 |
Secondary antibody, IF (1:1000) |
Antibody |
Anti-Mouse IgG1 Alexa Fluor 546 (Goat polyclonal) |
Thermo Fisher Scientific |
Cat #: A-21123 |
Secondary antibody, IF (1:1000) |
Other |
Vectashield Antifade |
Vector Laboratories |
Cat #: H-1000–10 |
Mounting medium |
Other |
AAV9-PHP.B- CMV-Tmc1e × 1 |
Wu et al., 2021
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Nucleic acid, Titer: 3.9 E + 13 gc/mL |
Software, algorithm |
Imaris |
https://imaris.oxinst.com/
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Software, algorithm |
ImageJ software |
http://imagej.nih.gov/ij/
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Software, algorithm |
Eaton-Peabody Laboratories Cochlear Function Test Suite |
https://www.masseyeandear.org/research/otolaryngology/eaton-peabody-laboratories/engineering-core
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