Table 1. Univariate analysis and multivariate analysis of overall survival by Cox’s Proportional Hazard model.

Univariate analysis
Parameters	Hazard ratio	95% CI		P value
ARL4C(low/high)	3.51	1.06	11.70	0.040
Sex(Male/Female)	1.10	0.54	2.24	0.80
Age( < 65/≧65)	1.05	0.47	2.35	0.91
Tumor Location(Head/Body or Tail)	0.41	0.18	0.94	0.036
pStage(IA-IIA/IIB-III)	2.51	1.17	5.41	0.019
pT(1-2/3)	5.29	1.23	22.70	0.025
pN(0/1)	2.51	1.17	5.41	0.019
ly(0/1–3)	2.74	1.17	6.46	0.021
v(0/1–3)	2.05	1.00	4.20	0.049
ne(0/1–3)	28,258	5.25E-36	1.52E + 44	0.83
Multivariate analysis
Parameters	Hazard ratio	95% CI		P value
pT(1-2/3)	3.72	0.78	17.7	0.099
pN(0/1)	1.80	0.79	4.10	0.16
ARL4C(low/high)	3.56	1.03	12.3	0.044

Hazard ratios with 95 % confidence intervals (CIs) were calculated using a Cox regression model and P values were calculated using a log-rank test. CI, confidence interval; pT, primary tumor; pN, regional lymph node; ly, lymphatic invasion; v, venous invasion; ne, perineural invasion.