Table 4.
Five-Year Fracture Incidence by Tertile of Total Dietary Protein Intake: The Health, Aging, and Body Composition (Health ABC) Study
| Dietary Protein Tertile, % of Total Energy Intake | |||
|---|---|---|---|
| <13% (reference) | <13%–15% | ≥15% | |
| Fragility fracture (cases, n) | 49 | 42 | 45 |
| Base modela | 1.00 | 0.81 (0.54, 1.23) | 0.76 (0.50, 1.15) |
| Full modelb | 1.00 | 0.76 (0.50, 1.15) | 0.71 (0.45, 1.11) |
| Clinical vertebral fracture (cases, n) | 14 | 9 | 8 |
| Base modela | 1.00 | 0.64 (0.27, 1.49) | 0.52 (0.21, 1.26) |
| Full modelb | 1.00 | 0.49 (0.20, 1.19) | 0.36 (0.14, 0.97) |
| Hip fracture (cases, n) | 5 | 7 | 8 |
| Base modela | 1.00 | 1.60 (0.50, 5.13) | 1.61 (0.51, 5.04) |
| Full modelb | 1.00 | 1.51 (0.45, 5.06) | 1.82 (0.54, 6.11) |
| Non-hip, non-spine fracture (cases, n) | 30 | 26 | 29 |
| Base modela | 1.00 | 0.78 (0.46, 1.33) | 0.74 (0.44, 1.25) |
| Full modelb | 1.00 | 0.76 (0.44, 1.30) | 0.72 (0.41, 1.27) |
Data are presented as hazard ratios (95% confidence intervals).
aBase model adjusted for age, gender, race, study site, and energy intake (all measured at baseline). bFull model adjusted for age, gender, race, study site, smoking status, alcohol consumption, education, physical activity, body mass index, energy intake, osteoporosis medications, dietary calcium intake, calcium and vitamin D supplement use, estrogen therapy, cognitive function, osteoporosis diagnosis, Health ABC Physical Performance Battery, and falls in the prior 12 mo (all measured at baseline).