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. 2021 Jul 31;58(11):5459–5472. doi: 10.1007/s12035-021-02481-z

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Double immunofluorescence staining of CRF-R2 (a, d, g) and ENK (b, e, h) in the rat L4-L5 spinal cord. (a, b, c) Parasagittal sections of L4-L5 spinal cord of the rat show a network of CRF-R2-immunoreactive fibers overlapping with ENK and extending through the superficial laminae of the dorsal horn of the lumber spinal cord. Some fibers express only ENK. (d–i) Double immunofluorescence staining of coronal sections of spinal cord of the rat showing that CRF-R2-immunoreactive fibers overlap with ENK. Some fibers express ENK only. Bar = 20 μm