Table 1.
Natural product compounds and extracts used in this study along with reported lifespan extension. For compound
source information, see the “Methods” section
| Compound/extract | Lifespan extension |
|---|---|
| Allantoin | Worms [39] |
| Alpha-lipoic acid | Worms [40, 41], flies [42] |
| Ashwagandha root | Worms [43] |
| Berberine | Mice [44], flies [45] |
| Broccoli concentrate | - |
| Cardamonin | - |
| Celastrol | Worms [46] |
| Choline bitartrate | - |
| Coumaric Acid | - |
| Curcumin phytosome complex | - |
| Dong Quai | - |
| Ellipticine | - |
| Ginseng | - |
| Ginsenoside Rc | Worms [47] |
| Glucosamine | Mice and worms [48] |
| Grape seed #1 | - |
| Grape seed #2 | - |
| Green tea | Worms [49], flies [50, 51], mice – midlife effect in females [52] |
| Hesperidin | Yeast [53] |
| Hydroxytyrosol | - |
| Isoliquiritigenin | - |
| Licorice root | Worms [54] |
| Lutein | Flies [55] |
| Lycopene | - |
| Milk thistle | Worms [56] |
| N-acetyl L-cysteine | Worms [57], flies [58, 59], mice [60] |
| Olive fruit | - |
| Polygonum cuspidatum root | - |
| Pterocarpus marsupium | - |
| Quercetin | Worms [61, 62], flies [63] |
| Rutin | Flies [64], mice [65] |
| Turmeric | Flies [66] |
| Tyrosol | Worms [67] |
| Umbelliferone | - |
| Verbascoside | - |
| Withaferin A | Mice [68], flies [69] |