TABLE 1.

The rat primer sequences used in qPCR.

Gene	Stream	Sequence (5–3′)
Bmal1	Forward	TGG​CCA​GAG​TGA​ATG​CTT​TTG
	Reverse	CCT​GAC​TGG​CCT​GGA​ACT​TG
Clock	Forward	TGC​TGT​CCT​TAC​TGC​TTG​GT
	Reverse	TGG​CAA​AGT​GGT​GAT​ACC​TGA
Per1	Forward	GTG​CTC​CAG​GAT​CCC​ATC​TG
	Reverse	CTC​TGA​GAA​CCG​TGG​CTG​TT
Per2	Forward	GAC​CAT​CTG​TGT​GTC​ATC​TGG​A
	Reverse	CTC​ATG​TGG​CTT​CCC​CGT​TA
Cry1	Forward	TGC​GCA​TTT​CAC​ACA​CAC​TG
	Reverse	GAC​AGA​GGG​GTT​GTG​CAC​TT
Cry2	Forward	TAG​AAC​CCG​CAG​CAG​TAA​CC
	Reverse	GAC​ACA​TCT​ATT​CCA​GCC​TGC
Collagen II	Forward	CAC​GCC​TTC​CCA​TTG​TTG​AC
	Reverse	CCG​GAC​TGT​GAG​GTT​AGG​ATA​G
Aggrecan	Forward	CAG​ATG​GCA​CCC​TCC​GAT​AC
	Reverse	ACA​CAC​CTC​GGA​AGC​AGA​AG
MMP13	Forward	ACC​ATC​CTG​TGA​CTC​TTG​CG
	Reverse	TTC​ACC​CAC​ATC​AGG​CAC​TC
ADAMTS5	Forward	GTC​CAA​ATG​CAC​TTC​AGC​CAC​GAT
	Reverse	AAT​GTC​AAG​TTG​CAC​TGC​TGG​GTG
GAPDH	Forward	TTG​TAA​CCA​ACT​GGG​ACG​ATA​TGG
	Reverse	GAT​CTT​GAT​CTT​CAT​GGT​GCT​AGG